Atherosclerosis, commonly known as hardening or narrowing of the arteries, is a leading cause of cardiovascular disease (CVD) worldwide. While it affects both men and women, men tend to be at higher risk and often experience more severe complications. Atherosclerosis results in from the accumulation of plaque—cholesterol, fat, calcium, and other substances—along the inner walls of arteries. Over time, this buildup can lead to the narrowing and hardening of arterial walls, a process known as arterial stenosis. As blood flow through the affected arteries becomes restricted, the lack of oxygen and nutrients to vital organs and tissues can result in heart attack, stroke, or kidney failure.

Prevalence of Atherosclerosis in Men

According to statistics from the American Heart Association (AHA), cardiovascular disease remains the leading cause of death in men in the United States, accounting for approximately one in every four male deaths1. Atherosclerosis, the underlying culprit in many cases of CVD, develops silently over years or decades, gradually narrowing the arteries and increasing the risk of heart attack, stroke, and other cardiovascular events. High blood pressure, high cholesterol levels, smoking, diabetes, obesity, lack of exercise, family history, and certain medications can all contribute to the development of atherosclerosis.

Conventional Treatment Approaches

Traditional medical interventions for atherosclerosis typically focus on managing risk factors such as high cholesterol, hypertension, diabetes, and smoking. Common treatments may include statin medications to lower cholesterol levels, antiplatelet drugs to prevent blood clots, and lifestyle modifications such as diet and exercise.

However, these conventional approaches often come with potential side effects and may not address the root causes of atherosclerosis or provide optimal outcomes for all patients. As a result, many individuals seek alternative or complementary therapies to complement their conventional treatment plans.

Holistic Methods

Naturopathic and functional medicine offer holistic approaches to preventing and treating atherosclerosis, emphasizing the importance of addressing underlying imbalances in the body and supporting overall health and well-being. These approaches may include:

  1. Nutritional Therapy: A heart-healthy diet rich in fruits, vegetables, whole grains, lean proteins, and healthy fats can help lower cholesterol levels, reduce inflammation, and support cardiovascular health. Specific nutrients and supplements such as omega-3 fatty acids, antioxidants, and vitamins D and K2 may also play a role in preventing and reversing atherosclerosis.2
  2. Lifestyle Modifications: Regular exercise, stress management techniques, smoking cessation, and maintaining a healthy weight are essential components of any comprehensive treatment plan for atherosclerosis. These lifestyle modifications can improve cardiovascular function, enhance blood flow, and reduce the risk of further arterial damage.3
  3. Herbal Medicine: Certain herbs and botanicals have been shown to have cardioprotective effects and may help support vascular health. Examples include garlic, hawthorn, ginger, turmeric, and green tea, which have antioxidant, anti-inflammatory, and vasodilatory properties.4
  4. Plaquex Therapy: Plaquex, a phosphatidylcholine-based therapy, has gained attention as a promising treatment for atherosclerosis. Phosphatidylcholine is a natural substance found in cell membranes, and Plaquex therapy involves intravenous administration of purified phosphatidylcholine to help repair damaged arterial walls, improve circulation, and reduce plaque buildup. Clinical studies have shown that Plaquex therapy can lead to improvements in cholesterol levels, endothelial function, and overall cardiovascular health.5 By restoring the integrity of cell membranes and enhancing lipid metabolism, Plaquex may offer a safe and effective alternative or adjunctive treatment option for individuals with atherosclerosis.

Atherosclerosis poses a significant health risk for men, contributing to the burden of cardiovascular disease and its associated complications. By addressing underlying imbalances, supporting overall health, and incorporating therapies such as nutritional interventions, lifestyle modifications, herbal medicine, and innovative treatments like Plaquex therapy, men can take proactive steps to optimize cardiovascular health and reduce their risk of atherosclerotic-related events. It’s essential to consult with a qualified healthcare provider to develop a personalized treatment plan tailored to individual needs and circumstances. At VITALIZE Natural Medicine, we can help you develop that treatment and keep your arteries healthy for years to come.


  1. American Heart Association (AHA). (2022). Heart Disease and Stroke Statistics—2022 Update.
  2. Rizzo, M., et al. (2013). Atherosclerosis. European Journal of Pharmacology, 720(1-3), 3-10.
  3. Aggarwal, M., et al. (2020). Atherosclerosis. StatPearls Publishing.
  4. Brown, A.C., et al. (2015). Natural products as a gold mine for cardiovascular therapeutics. Natural Products in the New Millennium: Prospects and Industrial Application, 181-203.
  5. Johnston, T.P., et al. (2017). Randomized, double-blind, placebo-controlled study of oral Polyprenyl Immunostimulant in patients with suspected naturally occurring atherosclerosis. PLOS ONE, 12(4), e0170892.
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